How to
How are bacteriophages (phages) produced?
Three types of phages are used to prepare diluted solutions in a French hospital (ROMAIN LAFABREGUE / AFP / Getty) How are…
Author: Raphael Hans Lwesya
Raphael Hans Lwesya is a PhD researcher and science communicator focused on bacteriophages, microbiology, and bioinformatics. He is the founder of The Phage, a platform dedicated to phage research, news, protocols and job opportunities.
Know your phage
What Causes Phage Plaque Halo?
What is plaque halo? Plaque halo refers to the partial-turbid clearance surrounding the original phage-induced clearance of the bacterial lawn. Not every…
PHAGE THERAPY
How does a phage based vaccine work?
During the COVID-19 pandemic, many scientists investigated various types of vaccine production in the hopes of saving the world. Other effective vaccines…
PHAGE RESISTANCE
Is it possible for bacteria to develop bacteriophage resistance?
Bacteriophages are ancient viruses that exclusively parasitize bacteria. They are extremely diverse in their host range and they target bacteria of all…
Laboratory procedure
Phage Display technology and it’s Application
Phage display is a molecular biology technique where bacteriophages, viruses that infect bacteria, are genetically modified to express foreign proteins on their…
Synthetic Biology
Bioluminescence-based Reporter Bacteriophages: New Technology for Monitoring Microbes and Diseases
Bacteria and bacteriophage. Photo by Oxford (Article by Pete Wilton) In recent years, the development of bioluminescence-based reporter bacteriophages has revolutionized the monitoring…
AMR
The potential use of Bacteriophage Lysins In the Medical field
Structure of gram-negative bacteriophage lysin. credit Fischetti (2019) Phage lysins are specialized hydrolytic cell wall enzymes that are used to rupture phage-infected bacteria…
AMR
Are Phages Microbiome-Friendly Therapeutic Approach?
Introduction Antibiotics are the most frequently prescribed class of drugs in the US and many other parts of the world. However, they…
Synthetic Biology
Can the Bacteriophage Mutants be the Next Generation Carriers for Conjugate Vaccines?
Passing through several waves of the deadly pandemic brought the human race into consideration of doing extensive research on vaccines. It is…
AMR
How do bacteriophages transfer antibiotic resistance genes (ARGs)?
An illustration of ARG transfer by T bacteriophages Because of the rise in antibiotic resistance, effective prevention of pathogens is becoming a…