Recently, Amazon has published an article on Phagos. Phagos an AI tech-bio start-up company, has utilized Amazon Web Services(AWS) to develop an AI model. With this AI model, performing phage-host matching becomes a lot easier. The phage therapy currently involves isolating specific phages from the environment, identifying those effective against a particular pathogenic bacterium, and then cultivating these selected phages, which is time-consuming.
“Everything had to be done by hand,” said Alexandros Pantalis, Co-founder & CEO at Phagos. “You had to screen every single phage against every single bacterial strain. And then, every phage combination against every target bacterial strain combination. It’s an exponential problem, and one that’s impossible to solve manually.”
Paving the way to precision medicine, the use of generative AI, along with Amazon Web Services (AWS), has accelerated phage prediction. Having been selected for the 2024 AWS Generative AI Accelerator Program, Phagos derived data from public databases and its lab-generated data. Phagos’s AI models will predict which phages are the most effective against any given infection, without the need for exhaustive trial and error.
The team initially working on Oysters has expanded to shrimp, chicken, and now to the bovine and swine industries, dissolving phages in drinking water to deliver a simple, scalable solution. With a mission to resolve bacterial infections, the entire technological development of the company is data-driven and based on machine learning.
Discovering novel phage genes and guiding the development of synthetic therapeutic phages using AI to tackle antimicrobial resistance across various industries is now the mission of Phagos.
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